Endocrine Abstracts

IntroductionParathyroid carcinoma is a very rare phenomenon with an estimated prevalence of 0.005% of all cancers. There have been fewer than ten cases of parathyroid carcinoma in pregnancy previously reported in literature. Clinical features are similar to primary hyperparathyroidism and the diagnosis is usually made on surgery or histology. We present a unique case of parathyroid carcinoma in pregnancy where ventricular bigeminy was the presenting feat...

This 22 year old lady presented with Haemophilus Influenza meningitis. Given an unusual organism, she had an MRI which revealed an incidental pituitary macroadenoma extending into the right cavernous sinus and breaching the anterioinferior wall of the pituitary fossa. Thyroid function showed raised T4 (24.7 pmol/L) and T3 (8.3 pmol/L) with unsuppressed TSH (1.75 munit/L). IGF-1 was also raised at 56.7 nmol/L (12–50.1 nmol/L).<p c...

This 22 year old lady presented with Haemophilus Influenza meningitis. Given an unusual organism, she had an MRI which revealed an incidental pituitary macroadenoma extending into the right cavernous sinus and breaching the anterioinferior wall of the pituitary fossa. Thyroid function showed raised T4 (24.7 pmol/L) and T3 (8.3 pmol/L) with unsuppressed TSH (1.75 munit/L). IGF-1 was also raised at 56.7 nmol/L (12–50.1 nmol/L).<p c...

Acute fatty liver of pregnancy (AFLP) is a rare obstetric metabolic emergency (UK incidence 1/20.000 maternities) which typically presents in 3rd trimester or postpartum and has a high maternal and foetal mortality and morbidity (UK Maternal mortality 1.8%, perinatal mortality 104/1000 births). Diagnosis can be delayed due to lack of set diagnostic criteria, rarity and overlapping clinical presentation with many other obstetric metabolic pathologies. Urgent delivery...

Thyroid uptake scan is a widely used thyroid investigation that provides valuable information regarding the structure and function of the gland and helps in differentiating some of the common thyroid pathologies. We present a multicentre audit of thyroid uptake scans done for non-malignant thyroid pathologies and try to analyse the usefulness of this investigation in different situations.MethodsThis audit includes thyroid uptake sc...

Transsphenoidal adenomectomy (TSA) is the recommended primary therapy in most patients with acromegaly and results in remission for majority of microadenomas and a proportion of macroadenomas depending on extent of surgically accessible disease. Acromegaly is associated with significant mortality and morbidity, hence a combination of treatment modalities may be needed to achieve disease control.Methods: A retrospective casenotes review was conducted and ...

We would like to report an interesting case of Graves’ disease which presented with thymic hyperplasia, bilateral generalised lymphadenopathy and hypercalcaemia, along with other typical manifestations of hyperthyroidism. A 53 year old lady was admitted following an opioid overdose as she was suffering from depression after a recent slipped disc injury which had resulted in poor mobility. She suffered an out of hospital respiratory arrest, underwent cardiopulmonary resusc...